Abstract : A retrospective study of bacterial isolates from pus and their susceptibility pattern was done among patients at Teule Designated District Hospital, Muheza, Tanzaniafrom October 2015 to August 2016. A total of 156 bacterial isolates were reviewed on the basis of their susceptibility pattern. Of these, 59 (37.82%) were Staphylococcus aureus followed by Proteus mirabilis 21 (13.46%), Coliforms 19 (12.17%), Pseudomonas aeruginosa 15 (9.61%), Escherichia coli 12 (7.69%) Klebsiella pneumonia 5 (3.20%), Acinetobacter species 3(1.92%), Streptococcus pyogenes 4 (2.56%), Klebsiella oxytoca 1 (0.64%) and mixed organisms 17 (10.89%). The sensitivity pattern showed that those sensitive to ciprofloxacin were 128 (92.8%), gentamicin 117 (81.3%) and ceftriaxone 50 (69.4%) while others where resistant to tetracycline 40 (67.6%), clotrimoxazole 82 (64.6%) and erythromycin 39 (57.4%). The study reveals that S. aureus is the leading cause in pus isolates. Ciprofloxacin (p = 0.5), gentamicin (p =0.05) and ceftazidime (p = 0.02) are the most effective and can be used empirically in treating these conditions though only gentamicin and ceftazidime are showing statistical significance. Resistance shown to erythromycin, tetracycline, ampicillin and cotrimoxazole may be due to being used over a much longer period of time and to indiscriminate use by health professionals.

Keyword : Muheza, Designated District Hospital, Antibiogram, Mixed organisms, Coliforms.