Abstract : Drug absorption is an important criteria for pharmacokinetic and pharmacodynamics action of drug. Various approaches to evaluate drug absorption potential include in silico models, in vitro models, ex-vivo models, in situ and in vivo models. The procedures, advantages, disadvantages for various screening models are discussed in this review.
Keywords: Absorption, permeability, ex-vivo, in-situ, in-vivo
Abstract : Rheumatoid arthritis (RA) is an autoimmune disorder mainly affects synovial joints. RA is a most common in females than male. It is mainly characterized by the Pain, stiffness of joints associated with fever, weakness etc. A melodramatic shift in drug discovery brings a noteworthy change in RA management. But these medicines having their own adverse effects on prolonged use. In recent days it has been seen that health professional community looking towards evidence-based alternative as well as complementary therapies to manage chronic disease conditions like RA. Such an integrative approach is definitely helpful in improving pain pattern as well as lifestyle in RA patients.
Keywords: Rheumatoid arthritis, Complementary and alternative therapies, Integrative medicine
Keyword : Rheumatoid arthritis, Complementary and alternative therapies, Integrative medicine
Abstract : Parenthood is perhaps the most important responsibility that one can undertakes in his/ her life , yet many young couples become parents without much preparation. Ayurveda, the ancient science gives importance to swasthya rakshana and vikara prashamana by exploring various procedures like dinacharya, ritucharya, sadvrutta for maintaining the physical and mental health and preventing the disease. Acharyas were still ahead in the field of prasuti tantra. Wide range of references regarding preconceptional care, garbhini paricharya, masanumasika pathya, contraindications for garbhini, guidelines for the management of prasuta stree are available in brihatrayi and laghutrayi. This paper tries to incorporate the relevance of preconceptional care in our society.
Keyword : ideal progeny, preconception care, healthy society
Abstract : ABSTRACT
Background: Pregnancy is one of the most dangerous experiences that women go through in life because of the associated complications. However, in Ghana, majority of pregnant women still do not access antenatal care services.
Methods: A cross-sectional survey was conducted among 489 pregnant and lactating mothers on their antenatal care services utilization. Data was collected using structured questionnaire through face-to-face interviews. Data was entered, cleaned and analyzed using SPSS version 20.
Results: In total, 88.1% of the women utilized antenatal care services. In the multivariate analysis, the following determinants were significantly associated with the likelihood of not utilizing antenatal care services (Odds Ratio (AOR) larger than 1): age of women, >35 years (AOR = 0.14, 95%CI = 0.08–0.97) compared to less than 20 years, educational level (compared to no formal education: tertiary level AOR = 0.19, 95%CI = 0.13–0.68), marital status (compared to single/never married: being married AOR = 0.23, 95%CI = 0.15–0.98), gravid (compared to primigravida: multigravida AOR = 0.37, 95%CI = 0.15–0.81) and ownership of National Health Insurance card (compared to having the card: not having the card AOR = 14.43, 95%CI = 3.04–48.33). women aged >35 years, married, tertiary level of education and multigravida were more likely to utilize antenatal care services, while women who do not have National Health Insurance cards were more likely not to utilize antenatal care services.
Conclusion: Antenatal care service utilization rate was below the regional target of 90%. Five factors were found to be associated with antenatal care service utilization. More effort is needed to reach the disadvantaged populations with antenatal care services.
Keyword : Antenatal care, Utilization, Predictors, Upper West Region, Ghana